Domilise's Po-Boy & Bar

Domilise's is a corner sandwich shop and bar in uptown New Orleans known for its po-boys, especially fried shrimp, oyster, roast beef and sausage versions served on Leidenheimer bread. The business began around 1918 as a neighborhood bar and later began serving plate lunches to dockworkers, and it has stayed in the same family for generations.

The shop keeps short weekday hours at lunchtime, with a later close on Thursday through Saturday, and it is closed on Sundays. Lines often form at the corner of Annunciation and Bellecastle during the lunch rush, so arriving early helps. Domilise's sits at 5240 Annunciation Street, and the family has long been known for treating every customer like family.